Advances of mesenchymal stem cells transplantation for treating intervertebral disc degeneration

Advances of mesenchymal stem cells transplantation for treating intervertebral disc degeneration

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2007 May;21(5):502-6
Authors: Liang T, Liu H
OBJECTIVE: To introduce the research of mesenchymal stem cells(MSCs) transplantation for treating intervertebral disc degeneration.
METHODS: The recent original articles about the MSCs transplantation for treating intervertebral disc degeneration were extensively reviewed.
RESULTS: Transplanted MSCs in intervertebral disc can express chrondcyte-like phenotype in certain conditions, increase matrix synthesis and release intervertebral disc degeneration.
CONCLUSION: MSCs transplantation for treating intervertebral disc degeneration may be a future approach.
PMID: 17578291 [PubMed – indexed for MEDLINE]

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