Article Citations

Nguyen AGuo JBanyard DAFadavi DToranto JDWirth GA,
Paydar KZEvans GR, Widgerow AD. Stromal vascular fraction:
A regenerative reality? Part 1: Current concepts and review of
the literature. J Plast Reconstr Aesthet Surg. 2016 Feb;69(2):170-9.
doi: 10.1016/j.bjps.2015.10.015. Epub 2015 Oct 31.
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Guo JNguyen ABanyard DAFadavi DToranto JDWirth GAPaydar KZ,
Evans GRWidgerow AD. Stromal vascular fraction: A regenerative reality?
Part 2: Mechanisms of regenerative action. J Plast Reconstr Aesthet Surg.
2016 Feb;69(2):180-8. doi: 10.1016/j.bjps.2015.10.014. Epub 2015 Oct 24.
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Zuk PA, Zhu M, Mizuno H, et al. Multilineage cells from human
adipose tissue: implications for cell-based therapies. Tissue
Eng 2001;7(2):211e28.
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Yoshimura K, Sato K, Aoi N, Kurita M, Hirohi T, Harii K. Cellassisted
lipotransfer for cosmetic breast augmentation: supportive
use of adipose-derived stem/stromal cells. Aesthetic
Plast Surg 2008;32(1):48e55 [discussion 56-7].
Click here to download PDF for free
 
Li J, Gao J, Cha P, et al. Supplementing fat grafts with adipose
stromal cells for cosmetic facial contouring. Dermatol Surg
2013;39(3 Pt 1):449e56.
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van Dijk A, Naaijkens BA, Jurgens WJ, et al. Reduction of
infarct size by intravenous injection of uncultured adipose
derived stromal cells in a rat model is dependent on the time
point of application. Stem Cell Res 2011;7(3):219e29.
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Atalay S, Coruh A, Deniz K. Stromal vascular fraction improves
deep partial thickness burn wound healing. Burns 2014;40(7):
1375e83.
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Chung MT, Zimmermann AS, Paik KJ, et al. Isolation of human
adipose-derived stromal cells using laser-assisted liposuction
and their therapeutic potential in regenerative medicine. Stem
cells Transl Med 2013;2(10):808e17.
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You HJ, Han SK. Cell therapy for wound healing. J Korean Med
Sci 2014;29(3):311e9.
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Jarajapu YP, Grant MB. The promise of cell-based therapies for
diabetic complications: challenges and solutions. Circ Res
2010;106(5):854e69.
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Tocco I, Widgerow AD, Lalezari S, Banyard D, Shaterian A,
Evans GR. Lipotransfer: the potential from bench to bedside.
Ann Plast Surg 2014;72(5):599e609.
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Kakagia D, Pallua N. Autologous fat grafting: in search of the
optimal technique. Surg Innov 2014;21(3):327e36.
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Kolle SF, Fischer-Nielsen A, Mathiasen AB, et al. Enrichment of
autologous fat grafts with ex-vivo expanded adipose tissuederived
stem cells for graft survival: a randomised placebocontrolled
trial. Lancet 2013;382(9898):1113e20.
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SumiM, Sata M,Toya N,Yanaga K,OhkiT, Nagai R. Transplantation
of adipose stromal cells, but not mature adipocytes, augments
ischemia-induced angiogenesis. Life Sci 2007;80(6):559e65.
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Zeyda M, Farmer D, Todoric J, et al. Human adipose tissue
macrophages are of an anti-inflammatory phenotype but
capable of excessive pro-inflammatory mediator production.
Int J Obes (Lond) 2007;31(9):1420e8.
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Tiemessen MM, Jagger AL, Evans HG, van Herwijnen MJ, John S,
Taams LS. CD4þCD25þFoxp3þ regulatory T cells induce alternative
activation of human monocytes/macrophages. Proc Natl
Acad Sci U S A 2007;104(49):19446e51.
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Corselli M, Crisan M, Murray IR, et al. Identification of perivascular
mesenchymal stromal/stem cells by flow cytometry.
Cytom A 2013;83(8):714e20.
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Choi JS, Kim BS, Kim JY, et al. Decellularized extracellular
matrix derived from human adipose tissue as a potential
scaffold for allograft tissue engineering. J Biomed Mater Res A
2011;97(3):292e9.
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Eckes B, Nischt R, Krieg T. Cell-matrix interactions in dermal
repair and scarring. Fibrogenes Tissue Repair 2010;3:4.
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Traktuev DO, Prater DN, Merfeld-Clauss S, et al. Robust functional
vascular network formation in vivo by cooperation of
adipose progenitor and endothelial cells. Circ Res 2009;
104(12):1410e20.
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Dominici M, Le Blanc K, Mueller I, et al. Minimal criteria for
defining multipotent mesenchymal stromal cells. The International
Society for Cellular Therapy position statement. Cytotherapy
2006;8(4):315e7.
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Sidney LE, Branch MJ, Dunphy SE, Dua HS, Hopkinson A.
Concise review: evidence for CD34 as a common marker for
diverse progenitors. Stem Cells 2014;32(6):1380e9.
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Corselli M, Crisan M, Murray I, et al. Identification of perivascular
mesenchymal stromal/stem cells by flow cytometry.
Cytom Part A 2013;83A:714e20.
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Hager G, Holnthoner W, Wolbank S, et al. Three specific antigens
to isolate endothelial progenitor cells from human liposuction
material. Cytotherapy 2013;15(11):1426e35.
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Navarro A, Marı´n S, Riol N, Carbonell-Uberos F, Min˜ana M. Human
adipose tissue-resident monocytes exhibit an endothelial-like
phenotype and display angiogenic properties. Stem Cell Res
Ther 2014;5(50):1e14.
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Blaber SP, Webster RA, Hill CJ, et al. Analysis of in vitro
secretion profiles from adipose-derived cell populations. J
Transl Med 2012;10:172.
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Chazenbalk G, Bertolotto C, Heneidi S, et al. Novel
pathway of adipogenesis through cross-talk between
adipose tissue macrophages, adipose stem cells and
adipocytes: evidence of cell plasticity. PLoS One 2011;6(3):e17834.
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Cianfarani F, Toietta G, Di Rocco G, Cesareo E,
Zambruno G, Odorisio T. Diabetes impairs adipose
tissue-derived stem cell function and efficiency in
promoting wound healing. Wound Repair Regen 2013;21(4):545e53.
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Yoshimura K, Sato K, Aoi N, Kurita M, Hirohi T, Harii K.
Cellassisted lipotransfer for cosmetic breast augmentation:
supportive use of adipose-derived stem/stromal cells.
Aesthetic Plast Surg 2008;32(1):48e55. discussion 56-7.
Click here to download PDF for free
 
Atalay S, Coruh A, Deniz K. Stromal vascular fraction
improves deep partial thickness burn wound healing.
Burns 2014 Nov; 40(7):1375e83.
Click here to purchase article
 
Chung MT, Paik KJ, Atashroo DA, et al. Studies in fat grafting:
part I. Effects of injection technique on in vitro fat viability
and in vivo volume retention. Plast Reconstr Surg 2014 Jul;
134(1):29e38.
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Koh YJ, Koh BI, Kim H, Koh BI, Kim H, et al. Stromal vascular
fraction from adipose tissue forms profound vascular network
through the dynamic reassembly of blood endothelial cells.
Arterioscler Thromb Vasc Biol 2011;31(5):1141e50.
Click here to download PDF for free
 
Rehman J, Traktuev D, Li J, et al. Secretion of angiogenic and
antiapoptotic factors by human adipose stromal cells. Circulation
2004;109(10):1292e8.
Click here to download PDF for free
 
Kolle SF, Fischer-Nielsen A, Mathiasen AB, et al. Enrichment of
autologous fat grafts with ex-vivo expanded adipose tissuederived
stem cells for graft survival: a randomised placebocontrolled
trial. Lancet 2013;382(9898):1113e20.
Click here to purchase article
 
Armulik A, Abramsson A, Betsholtz C. Endothelial/pericyte
interactions. Circ Res 2005;97(6):512e23.
Click here to download PDF for free
 
Kwon HM, Hur SM, Park KY, et al. Multiple paracrine factors
secreted by mesenchymal stem cells contribute to angiogenesis.
Vasc Pharmacol 2014 Oct;63(1):19e28.
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Zhu M, Dong Z, Gao J, et al. Adipocyte regeneration after free
fat transplantation: promotion by stromal vascular fraction
cells. Cell Transpl 2015;24(1):49e62.
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Fu S, LuanJ, XinM,WangQ,Xiao R,Gao Y. Fate of adipose-derived
stromal vascular fraction cells after co-implantation with fat
grafts: evidence of cell survival and differentiation in ischemic
adipose tissue. Plast Reconstr Surg 2013;132(2):363e73.
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Paik KJ, Zielins ER, Atashroo DA, et al. Studies in fat grafting:
part V. Cell-assisted lipotransfer to enhance fat graft retention
is dose dependent. Plast Reconstr Surg 2015;136(1):67e75.
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Klar AS, Guven S, Biedermann T, et al. Tissue-engineered
dermo-epidermal skin grafts prevascularized with adiposederived
cells. Biomaterials 2014;35(19):5065e78.
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Barba M, Cicione C, Bernardini C, Michetti F, Lattanzi W. Adipose-
derived mesenchymal cells for bone regereneration:
state of the art. Biomed Res Int 2013;2013:416391.
Click here to download PDF for free
 
di Summa PG, Kingham PJ, Raffoul W, Wiberg M, Terenghi G,
Kalbermatten DF. Adipose-derived stem cells enhance peripheral
nerve regeneration. J Plast Reconstr Aesthet Surg 2010;
63(9):1544e52.
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You HJ, Han SK. Cell therapy for wound healing. J Korean Med
Sci 2014;29(3):311e9.
Click here to download PDF for free
 
Han SK, Kim HR, Kim WK. The treatment of diabetic foot ulcers
with uncultured, processed lipoaspirate cells: a pilot study.
Wound Repair Regen 2010;18(4):342e8.
Click here to purchase article
 
Pereira Lopes FR, Lisboa BC, Frattini F, et al. Enhancement of
sciatic nerve regeneration after vascular endothelial growth
factor (VEGF) gene therapy. Neuropathol Appl Neurobiol 2011;
37(6):600e12.
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Badylak SF. The extracellular matrix as a scaffold for tissue
reconstruction. Semin Cell Dev Biol 2002;13(5):377e83.
Click here to purchase article
 
Bosman FT, Stamenkovic I. Functional structure and composition
of the extracellular matrix. J Pathol 2003;200(4):423e8.
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Alberts B. Molecular biology of the cell. 4th ed., New York:
Garland Science; 2002. xxxiv, 1548.
 
Sheetz MP, Felsenfeld DP, Galbraith CG. Cell migration: regulation
of force on extracellular-matrix-integrin complexes.
Trends Cell Biol 1998;8(2):51e4.
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Friedl P, Zanker KS, Brocker EB. Cell migration strategies in 3-D
extracellular matrix: differences in morphology, cell matrix
interactions, and integrin function. Microsc Res Tech 1998;
43(5):369e78.
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Bauer AL, Jackson TL, Jiang Y. Topography of extracellular
matrix mediates vascular morphogenesis and migration speeds
in angiogenesis. PLoS Comput Biol 2009;5(7):e1000445.
Click here to download PDF for free
 
Choi JS, Yang HJ, Kim BS, et al. Human extracellular matrix (ECM)
powders for injectable cell delivery and adipose tissue
engineering. J Control Release 2009;139(1):2e7.
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  1. Debels, Gerrand YW, Poon CJ, Abberton KM, Morrison WA,

Mitchell GM. An adipogenic gel for surgical reconstruction of
the subcutaneous fat layer in a rat model, J Tissue Eng Regen
Med, http://dx.doi.org/10.1002/term.2025. Online Version of
Record published before inclusion in an issue
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Choi JH, Bellas E, Vunjak-Novakovic G, Kaplan DL. Adipogenic
differentiation of human adipose-derived stem cells on 3D silk
scaffolds. Methods Mol Biol 2011;702:319e30.
Click here to download free PDF
 
Chernousov MA, Yu WM, Chen ZL, Carey DJ, Strickland S.
Regulation of Schwann cell function by the extracellular matrix.
Glia 2008;56(14):1498e507.
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Brown BN, Londono R, Tottey S, et al. Macrophage phenotype
as a predictor of constructive remodeling following the implantation
of biologically derived surgical mesh materials. Acta
Biomater 2012;8(3):978e87.
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Mills S, Cowin A, Kaur P. Pericytes, mesenchymal stem
cells and the wound healing process. Cells 2013;2(3):621e34.
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Caplan AI, Correa D. The MSC: an injury drugstore. Cell Stem
Cell 2011;9(1):11e5.
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Narayanan A, Page R, Swanson J. Collagen synthesis by human fibroblasts
Regulation by transforming growth factor-fl in the presence of other
inflammatory mediators. Biochem J 1989;260:463e9.
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Newman AC, Nakatsu MN, Chou W, Gershon PD, Hughes CC. The
requirement for fibroblasts in angiogenesis: fibroblast-derived
matrix proteins are essential for endothelial cell lumen formation.
Mol Biol Cell 2011;22(20):3791e800.
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Newman AC, Chou W, Welch-Reardon KM, et al. Analysis of
stromal cell secretomes reveals a critical role for stromal
cellederived hepatocyte growth factor and fibronectin in
angiogenesis. Arterioscler Thromb Vasc Biol 2013;33:
513e22.
Click here to download free PDF
 
Bianchi F, Maioli M, Leonardi E, et al. A new nonenzymatic
method and device to obtain a fat tissue derivative highly
enriched in pericyte-like elements by mild mechanical
forces from human lipoaspirates. Cell Transpl 2013;22(11):
2063e77.
Click here to access free PDF
 
Traktuev DO, Merfeld-Clauss S, Li J, et al. A population of
multipotent CD34-positive adipose stromal cells share pericyte
and mesenchymal surface markers, reside in a periendothelial
location, and stabilize endothelial networks. Circ Res 2008;
102(1):77e85.
Click here to download free PDF
 
Eto H, Ishimine H, Kinoshita K, et al. Characterization of
human adipose tissue-resident hematopoietic cell populations
reveals a novel macrophage subpopulation with CD34 expression
and mesenchymal multipotency. Stem Cells Dev 2013;
22(6):985e97.
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Karacaoglu E, Kizilkaya E, Cermik H, Zienowicz R. The role of
recipient sites in fat-graft survival: experimental study. Ann
Plast Surg 2005;55(1):63e8 [discussion 68].
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Matsumoto D, Sato K, Gonda K, et al. Cell-Assisted lipotransfer:
supportive use of human adipose-derived cells for soft tissue
augmentation with lipoinjection. Tissue Eng 2006;12(6):
3375e89.
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Tanikawa DY, Aguena M, Bueno DF, Passos-Bueno MR, Alonso N.
Fat grafts supplemented with adipose-derived stromal cells in
the rehabilitation of patients with craniofacial microsomia.
Plast Reconstr Surg 2013;132(1):141e52.
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Peltoniemi HH, Salmi A, Miettinen S, et al. Stem cell enrichment
does not warrant a higher graft survival in lipofilling of
the breast: a prospective comparative study. J Plast Reconstr
Aesthet Surg 2013;66(11):1494e503.
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Kakudo N, Tanaka Y, Morimoto N, et al. Adipose-derived
regenerative cell (ADRC)-enriched fat grafting: optimal cell
concentration and effects on grafted fat characteristics. J
Transl Med 2013;11:254.
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Kamakura T, Ito K. Autologous cell-enriched fat grafting for
breast augmentation. Aesthetic Plast Surg 2011;35(6):
1022e30.
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Chatterjee S, Laliberte M, Blelloch S, et al. Adipose-derived
stromal vascular fraction differentially expands breast progenitors
in tissue adjacent to tumors compared to healthy
breast tissue. Plast Reconstr Surg 2015;136(4):414ee25e.
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Mandel K, Yang Y, Schambach A, Glage S, Otte A, Hass R.
Mesenchymal stem cells directly interact with breast cancer
cells and promote tumor cell growth in vitro and in vivo. Stem
Cells Dev 2013;22(23):3114e27.
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Rowan BG, Gimble JM, Sheng M, et al. Human adipose tissuederived
stromal/stem cells promote migration and early
metastasis of triple negative breast cancer xenografts. PloS
One 2014;9(2):e89595.
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Zimmerlin L, Donnenberg AD, Rubin JP, Basse P,
Landreneau RJ, Donnenberg VS. Regenerative therapy and
cancer: in vitro and in vivo studies of the interaction between
adipose-derived stem cells and breast cancer cells from clinical
isolates. Tissue Eng Part A 2011;17(1-2):93e106.
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Charles-de-Sa L, Gontijo-de-Amorim NF, Maeda Takiya C,
et al. Antiaging treatment of the facial skin by fat graft and
adipose-derived stem cells. Plast Reconstr Surg 2015;135(4):
999e1009.
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Bourin P, Bunnell BA, Casteilla L, et al. Stromal cells from
the adipose tissue-derived stromal vascular fraction and
culture expanded adipose tissue-derived stromal/stem cells:
a joint statement of the International Federation for Adipose
Therapeutics and Science (IFATS) and the International
Society for Cellular Therapy (ISCT). Cytotherapy 2013;15(6):
641e8.
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Banyard DA, Salibian AA, Widgerow AD, Evans GR. Implications
for human adipose-derived stem cells in plastic surgery. J Cell
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FDA.gov. Human cells, tissues, and cellular and tissue-based
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Gir P, Oni G, Brown SA, Mojallal A, Rohrich RJ. Human adipose
stem cells: current clinical applications. Plast Reconstr Surg
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Liras A. Future research and therapeutic applications of human
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Tonnard P, Verpaele A, Peeters G, Hamdi M, Cornelissen M,
Declercq H. Nanofat grafting: basic research and clinical applications.
Plast Reconstr Surg 2013;132(4):1017e26.
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Stuzin JM. Discussion: Nanofat grafting: basic research and
clinical applications. Plast Reconstr Surg 2013;132(4):
1027e8.
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di Summa PG, Kingham PJ, Raffoul W, Wiberg M, Terenghi G,
Kalbermatten DF. Adipose-derived stem cells enhance peripheral
nerve regeneration. J Plast Reconstr Aesthet Surg 2010;
63(9):1544e52.
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Pereira Lopes FR, Camargo de Moura Campos L, Dias
Correa Jr J, et al. Bone marrow stromal cells and resorbable
collagen guidance tubes enhance sciatic nerve regeneration in
mice. Exp Neurol 2006;198(2):457e68.
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Mohammadi R, Sanaei N, Ahsan S, Rostami H, Abbasipour-
Dalivand S, Amini K. Repair of nerve defect with chitosan graft
supplemented by uncultured characterized stromal vascular
fraction in streptozotocin induced diabetic rats. Int J Surg
2014;12(1):33e40.
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Papalia I, Raimondo S, Ronchi G, Magaudda L, Giacobini-
Robecchi MG, Geuna S. Repairing nerve gaps by vein conduits
filled with lipoaspirate-derived entire adipose tissue hinders
nerve regeneration. Ann Anat 2013;195(3):225e30.
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Constantinescu CS, Farooqi N, O’Brien K, Gran B. Experimental
autoimmune encephalomyelitis (EAE) as a model for multiple
sclerosis (MS). Br J Pharmacol 2011;164(4):1079e106.
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Semon JA, Zhang X, Pandey AC, et al. Administration of murine
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Ricco JB, Thanh Phong L, Schneider F, et al. The diabetic foot:
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Han SK, Kim HR, Kim WK. The treatment of diabetic foot ulcers
with uncultured, processed lipoaspirate cells: a pilot study.
Wound Repair Regen 2010;18(4):342e8.
Click here to view Abstract on PubMed
 
Lv SS, Liu G, Wang JP, et al. Mesenchymal stem cells transplantation
ameliorates glomerular injury in streptozotocininduced
diabetic nephropathy in rats via inhibiting macrophage
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Perbeck L, Celebioglu F, Svensson L, Danielsson R. Lymph circulation
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Rigotti G, Marchi A, Galie M, et al. Clinical treatment of
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Gimble JM, Bunnell BA, Chiu ES, Guilak F. Concise review:
Adipose-derived stromal vascular fraction cells and stem cells:
let’s not get lost in translation. Stem Cells 2011;29(5):749e54.
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Laass MW, Roggenbuck D, Conrad K. Diagnosis and classification
of Crohn’s disease. Autoimmun Rev 2014;13(4-5):467e71.
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Dalal J, Gandy K, Domen J. Role of mesenchymal stem cell
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Thesleff T, Lehtimaki K, Niskakangas T, et al. Cranioplasty with
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Sandor GK, Tuovinen VJ, Wolff J, et al. Adipose stem cell tissue-
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Wilson SM, Goldwasser MS, Clark SG, et al. Adipose-derived
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Mehrkens A, Saxer F, Guven S, et al. Intraoperative engineering
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Jurgens WJ, Kroeze RJ, Zandieh-Doulabi B, et al. One-step
surgical procedure for the treatment of osteochondral defects
with adipose-derived stem cells in a caprine knee defect: a
pilot study. Biores Open Access 2013;2(4):315e25.
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Arana M, Gavira JJ, Pena E, et al. Epicardial delivery of
collagen patches with adipose-derived stem cells in rat and
minipig models of chronic myocardial infarction. Biomaterials
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Gimble JM, Katz AJ, Bunnell BA. Adipose-derived stem cells for
regenerative medicine. Circ Res 2007;100(9):1249e60.
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Yoshimura K, Shigeura T, Matsumoto D, et al. Characterization
of freshly isolated and cultured cells derived from the fatty
and fluid portions of liposuction aspirates. J Cell Physiol 2006;
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Yoshimura K. Cell-assisted lipotransfer for breast augmentation:
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