How Our Stem Cell Therapy Works
The body has two types of cells to respond to injury: stem cells and white blood cells. Stem cells help injuries heal naturally with like tissue, while white blood cells heal with scar tissue, leading to pain and decreased or lack of functionality.
Our technology helps doctors harness their patients’ own adipose derived stem cells, which are otherwise dormant and sequestered from the rest of the body in the adipose tissue and make these powerful, regenerative cells bio-available to help promote healing naturally.
In this new era of medicine, it’s critical that our work be tracked and analyzed so that we can best understand how to approach the many cellular conditions we’re faced with as physicians on a daily basis. Our database helps us make the best decision for patients and share our findings on a global level to advance personal cell therapy.
Understanding Stem Cells
Stem cells are cells that are able to either self-replicate, differentiate into other cell types, or act via a paracrine effect providing specific signals to injured or damaged cells. When we’re young, our bodies have much larger quantities of stem cells, which is why we heal quickly from injury. As we age, our native stem cell populations are depleted, and healing takes much longer, as it’s often not accomplished by stem cells but by white blood cells that result in scar tissue.
There are stem cells located throughout the body, but we choose to work with adipose derived stem cells for very specific reasons.
1.
Stem cells are cells that are able to either self-replicate, differentiate into other cell types, or act via a paracrine effect providing specific signals to injured or damaged cells. When we’re young, our bodies have much larger quantities of stem cells, which is why we heal quickly from injury. As we age, our native stem cell populations are depleted, and healing takes much longer, as it’s often not accomplished by stem cells but by white blood cells that result in scar tissue.
2.
Adipose derived stem cells are numerous. There are about 500 to 2,000 times more stem cells in your adipose tissue than your bone marrow. When trying to promote healing, we would like to have the greatest number of young, healthy cells and adipose gives us the best opportunity to do that.
3.
Most people are willing to donate a little bit of fat. We don’t need much, only a 50cc lipoaspirate. The extraction process is simple and easy, all performed under local anesthesia.
Harvesting Stem Cells
Stromal Vascular Fraction (SVF) is obtained via a mini-liposuction procedure done under local anesthesia. The procedure is simple and only requires a 50cc lipoaspirate.
Developed by Mark Berman MD, the former President of the American Academy of Cosmetic Surgery, our harvesting technique is different from traditional liposuction, which aims simply to remove and discard adipose tissue.
Our goal is different in that we are looking to secure the greatest number of healthy, viable adipose derived stem cells possible for deployment.
Customized Treatment Plan
Stem cell therapy should be one of the most exciting tools in a physician’s toolbelt in the 21st century. But one size does not fit all. CSN takes a multidisciplinary approach to stem cell therapy and works with physicians from all different kinds of backgrounds to make sure patients receive specialized care.
CSN has developed and deployed numerous IRB-approved protocols over the years but also can help physicians and clinics initiate their own as well.
Stem Cell Isolation and Administration
Once you have harvested your adipose sample, CSN’s latest technology allows physicians to automatically isolate stromal vascular fraction (SVF). This technology relies upon a cGMP medical-grade collagenase enzyme to chemically cut the collagen bonds in the adipose tissue and liberate the SVF cells from these bonds. The isolation process is compliant with FDA regulations 21CFR1271.
When the SVF has been isolated, it can be deployed in numerous ways depending on the patient’s needs and the physician’s specialty. CSN has published on the many different ways SVF has been deployed, including intravenous, intraarticular, intraventricular, and many more.